RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
mir-455
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; immunohistochemistry etc.
Target
CALRETICULIN
Pathway
NA
PubMed ID
Title
Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload
Year
2015
Function
"miR-455 replacement therapy markedly reduced myocardial fibrosis and inhibited apoptosis, suggesting that this therapy can prevent maladaptive ventricular remodeling."